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Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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Tactile and Chemical Senses01:27

Tactile and Chemical Senses

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Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
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Taste Buds and Receptors01:20

Taste Buds and Receptors

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Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
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Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

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The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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Introduction to Special Senses01:26

Introduction to Special Senses

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Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
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Related Experiment Video

Updated: Oct 14, 2025

Testing for Odor Discrimination and Habituation in Mice
06:41

Testing for Odor Discrimination and Habituation in Mice

Published on: May 5, 2015

18.2K

Sex Differences in Odor Hedonic Perception: An Overview.

Charlotte Bontempi1, Laurence Jacquot1, Gérard Brand1,2

  • 1Laboratoire de Recherches Intégratives en Neurosciences et Psychologie Cognitive - UR481, Université de Franche-Comté, Besançon, France.

Frontiers in Neuroscience
|November 4, 2021
PubMed
Summary
This summary is machine-generated.

Gender differences in odor perception are minimal for general smells but more pronounced for body odors. This review finds little evidence of gender-based variation in the hedonic judgment of odors, especially in psychiatric patients.

Keywords:
emotionhedonicityolfactionpleasantness ratingsex differences

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Area of Science:

  • Neuroscience
  • Sensory Perception
  • Psychology

Background:

  • Odor hedonic evaluation (pleasantness/unpleasantness) is a primary dimension of olfactory perception.
  • While sex differences in olfaction are well-researched, gender's impact on hedonic perception is less understood.
  • Existing studies use diverse methods, including psychophysical and psychophysiological measurements, to compare men and women.

Purpose of the Study:

  • To review experimental works on gender differences in odor hedonic perception.
  • To analyze findings for both non-specific and body odors.
  • To examine gender effects in healthy participants versus patients with psychiatric disorders.

Main Methods:

  • Systematic review of experimental studies comparing odor hedonic judgments between genders.
  • Categorization of studies based on odor type (non-specific vs. body odors).
  • Inclusion of studies comparing healthy individuals with psychiatric patient groups.

Main Results:

  • Overall literature suggests no significant gender differences in odor hedonic judgment, unlike differences in odor sensitivity, identification, or discrimination.
  • Gender effects are more apparent for body odors compared to non-specific odors.
  • Gender differences in hedonic judgment are rarely reported in individuals with psychiatric disorders.

Conclusions:

  • Gender has a limited impact on the hedonic judgment of odors, particularly for non-specific scents.
  • The influence of gender on odor pleasantness is more pronounced for body odors.
  • Findings are discussed concerning pleasantness rating mechanisms and emotional processing, with minimal gender influence noted in psychiatric conditions.