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Thromboembolism in Arthroplasty: Compliance to Prophylaxis
Leandra Marla Aires Travassos Viana1, Iara Antônia Lustosa Nogueira1, Andréa Martins Melo Fontenele2
1Setor de Farmácia, Unidade de Farmácia Clínica, Hospital Universitário, Universidade Federal do Maranhão, São Luís, MA, Brasil.
Revista Brasileira De Ortopedia
|November 4, 2021
Summary
Most patients (73%) undergoing knee or hip replacement showed high compliance with drug prophylaxis for preventing blood clots. Understanding and acceptance of prophylaxis significantly influenced patient adherence to medication.
Area of Science:
- Orthopedic Surgery
- Pharmacology
- Public Health
Background:
- Thromboembolism prophylaxis is crucial for patients undergoing knee or hip arthroplasty.
- Understanding patient compliance is essential for effective treatment outcomes.
- Adherence to anticoagulant medication impacts the prevention of post-operative complications.
Purpose of the Study:
- To determine the compliance profile for thromboembolism drug prophylaxis.
- To analyze factors influencing medication adherence in arthroplasty patients.
- To assess compliance rates at a public hospital setting.
Main Methods:
- Prospective cohort study conducted from August 2017 to September 2018.
- Utilized the eight-item Morisky Medication Adherence Scale for quantification.
- Categorized compliance as high (8 points), medium (6 to <8), and low (<6).
Main Results:
- 73.0% of patients exhibited high compliance with thromboprophylaxis.
- 27.0% of patients were classified as partially compliant.
- Higher compliance was observed in patients with good understanding and acceptance of prophylaxis, even with polypharmacy.
Conclusions:
- Patient understanding and acceptance of prophylaxis are key compliance drivers.
- Daily medication load, anticoagulant cost, and adverse reaction potential influence adherence.
- Targeted patient education can improve compliance with thromboembolism prophylaxis.
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