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Updated: May 12, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
RISK STRATIFICATION PROTOCOL FOR PERFORMING TOTAL KNEE ARTHROPLASTY
Fabrício Bolpato Loures1, Guilherme de Mattos Queiroz1, Danielle Lopes Rosa1
1Universidade Estadual do Rio de Janeiro (UERJ), Hospital Universitário Pedro Ernesto, Rio de Janeiro, RJ, Brazil.
Objective:
the main objective of the study was to evaluate a screening protocol for performing total knee arthroplasty (TKA) without postoperative admission to an intensive care unit (ICU). The secondary objective was to evaluate the postoperative blood transfusion rate.
Method:
between January 2020 and December 2021, 270 TKA were performed, following a clinical protocol: age up to 75 years, body mass index up to 35 kg/m2, ASA score classification I or II, non-smoker, without history of ischemic disease (coronary or cerebral), creatinine clearance greater than 60 mL/min, hemoglobin greater than 12 g/dL and osteoarthritis with deformity treatable with primary prosthesis (fixed or rotating base). The need for conversion to ICU and the blood transfusion rate were assessed.
Results:
270 patients underwent surgery during the study period and only one required admission to the ICU, giving the screening protocol a positive predictive value of 99.6%. There was no indication for blood transfusion in any case in the sample.
Conclusion:
The proposed screening protocol proved to be effective, allowing total knee arthroplasty to be performed without the prior need for ICU bed reservation, blood typing and/or blood products reservation, without compromising patient safety. Level of Evidence IV; Case Series .
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