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Pediatric Inflammatory Multisystem Syndrome or Multisystem Inflammatory Syndrome in Children: A New Thread in
Víctor Arízaga-Ballesteros1, Marissa Andrea Gutierrez-Mendoza1, Kinoa Rina Villanueva-Sugishima1
1Tecnológico de Monterrey, Monterrey, Mexico.
Insights
Pediatric inflammatory multisystem syndrome (PIMS) is a serious COVID-19 complication in children. This review covers PIMS epidemiology, clinical features, diagnosis, and treatment, including Latin American experiences.
Area of Science:
- Pediatric Infectious Diseases
- Public Health
- Virology
Background:
- The COVID-19 pandemic spurred global health efforts for SARS-CoV-2 prevention and treatment.
- Pediatric inflammatory multisystem syndrome (PIMS) has emerged as a significant medium-term complication of COVID-19 in children.
Purpose of the Study:
- To review current understanding of PIMS in children.
- To detail PIMS epidemiology, clinical presentation, and evolution.
- To outline diagnostic testing, interconsultation recommendations, and treatment strategies.
Main Methods:
- Comprehensive literature review of PIMS.
- Analysis of epidemiological data and clinical case studies.
- Synthesis of current diagnostic and therapeutic guidelines.
Main Results:
- PIMS definition, epidemiology, and clinical manifestations are presented.
- Recommended laboratory tests, diagnostic imaging, and specialist consultations are detailed.
- Treatment approaches and outcomes for PIMS are discussed, incorporating Latin American data.
Conclusions:
- PIMS requires prompt recognition and multidisciplinary management.
- Understanding PIMS evolution and treatment is crucial for pediatric COVID-19 care.
- Further research on PIMS long-term outcomes is warranted.
Abstract:
After the perturbing effects of the COVID-19 Pandemic, we observed intense public health efforts in a global-scale to prevent, control, and treat the SARS-CoV-2. Hundreds of clinical center researched for adequate treatments, other were devoted to the development the COVID-19 vaccines and other studied the nature and the effects of this mutant coronavirus SARS-CoV-2. As time goes by, the pediatric inflammatory multisystem syndrome has been recently defined and associated the COVID-19 past infection and is now considered a shot to middle-term complication of COVID-19. In this paper, we review the actual concepts of PIMS in children, the epidemiology, the clinical presentation, and evolution, the recommended laboratory and other testing. The recommended specialties interconsultation for hospitalized patients and a full discussion on the appropriate treatment of these patients. We include the Latin-American experience with PIMS and a final discussion on the outcome of this disease.
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