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Updated: Oct 14, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
Implementation of Privacy and Security for a Genomic Information System
Jaime Delgado1, Silvia Llorente1, Guillem Reig2
1Information Modeling and Processing (IMP) group - DMAG, Computer Architecture Dept. (DAC).
Secure access to genomic data is crucial for personalized medicine. This study introduces GIPAMS, a modular architecture using MPEG-G, to manage and protect sensitive genomic information effectively.
Area of Science:
- Genomics
- Bioinformatics
- Medical Informatics
Background:
- Personalized medicine relies heavily on genomic data.
- Genomic data access requires stringent privacy and security measures.
- Existing genomic data formats lack comprehensive security and metadata integration.
Purpose of the Study:
- To propose a secure and controlled architecture for accessing genomic information.
- To leverage the MPEG-G standard for enhanced genomic data management.
- To facilitate the advancement of personalized medicine through secure data handling.
Main Methods:
- Utilized the MPEG-G standard for its inherent metadata and protection features.
- Developed a modular architecture named GIPAMS (Genomic Information Protection and Access Management System).
- Implemented hierarchical data organization within the MPEG-G framework.
Main Results:
- GIPAMS provides a secure and controlled access mechanism for genomic data.
- The architecture effectively manages sensitive genomic information.
- Demonstrated the feasibility of using MPEG-G for secure genomic data storage and retrieval.
Conclusions:
- The GIPAMS architecture offers a robust solution for managing secure genomic data.
- This approach supports the secure implementation of personalized medicine.
- Enhanced data security and controlled access are vital for genomic data utilization.
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