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Updated: Oct 14, 2025

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
Aquatic Antagonists: Sea Cucumbers (Holothuroidea)
Carter R Ellis1, Dirk M Elston1, Juan Pedro Lonza Joustra1
1Drs. Ellis and Elston are from the Medical University of South Carolina, Charleston. Dr. Lonza Joustra is in independent practice, Iquique, Chile. Dr. Haddad is from the Department of Dermatology, Botucatu School of Medicine, Brazil.
Abstract:
Sea cucumbers are sausage-shaped aquatic creatures living on the ocean floors across the world. They are considered a food delicacy in many countries but also are known to have many beneficial pharmaceutical properties; however, sea cucumbers also contain a dangerous component called holothurin, which has been shown to have a negative impact on the health of both humans and other wildlife. In humans, exposure to holothurin can cause a painful irritant dermatitis, irritation of the mucous membranes, potential blindness, and, if ingested, even possible death. Treatment options include irrigation with seawater, soap, isopropyl alcohol, and vinegar.
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