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Published on: April 7, 2023
An innovative approach using microencapsulated turmeric oleoresin to develop ready-to-use turmeric milk powder with
Vinod S Ipar1, Rekha S Singhal2, Padma V Devarajan1
1Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, Maharashtra, India.
Abstract:
The use of phytochemicals for nutritional wellness has attracted worldwide attention and resulted in development of innovative formulations. Turmeric latte is one such formulation. However, an in-depth study on its physicochemical properties and oral bioavailability has not been conducted as yet. We present a ready-to-use turmeric latte by microencapsulating turmeric oleoresin (TO) with a blend of gum acacia, maltodextrin, and dairy whitener (DW) with bioenhancers by spray drying. The microencapsulated powder obtained exhibited >95% encapsulation efficiency, desired curcumin content, of 539.98 ± 6.56 to 706.40 ± 5.25 mg/100 g, wettability time below 40 s, and dispersibility above 95%. Turmeric latte released >95% of curcumin at pH 1.2 HCl with 0.1% Tween 80, which was ascribed in part to curcumin amorphization as evidenced by DSC and XRD. Turmeric latte demonstrated superior antioxidant activity with 4.2-fold enhanced permeability through non-everted rat intestine and 4.9-fold higher oral bioavailability in rats confirming bioenhancement.
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