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Updated: Oct 14, 2025
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Cyanoacrylate Securement in Neonatal PICC Use: A 4-Year Observational Study
Matheus van Rens1, Abdelghafar M A Nimeri, Timothy R Spencer
1Women's Wellness and Research Center, Hamad Medical Corporation, Doha, Qatar (Mr van Rens, Drs Nimeri and Mahmah, and Ms Francia); Global Vascular Access LLC, Scottsdale, Arizona (Mr Spencer); and Hamad Medical Corporation, Doha, Qatar (Dr Hugill and Dr. Olukade).
Background:
Within every neonatal clinical setting, vascular access devices are considered essential for administration of fluids, nutrition, and medications. However, use of vascular access devices is not without danger of failure. Catheter securement adhesives are being evaluated among adult populations, but to date, studies in neonatal settings are scant.
Purpose:
This research describes the prevalence of peripherally inserted central catheter failure related to catheter securement before and after the introduction of tissue adhesive for catheter securement. The identified modifiable risks might be used to evaluate efficacy, to innovate neonatal practice and support future policy developments.
Method And Setting:
This was a retrospective observational analysis of routinely collected anonymized intravenous therapy-related data. The study was carried out at the tertiary neonatal intensive care unit (112 beds) of the Women's Wellness and Research Center of Hamad Medical Corporation, Doha, Qatar.
Results:
The results showed that the use of an approved medical grade adhesive for catheter securement resulted in significantly less therapy failures, compared with the control group. This remains significant after adjusting for day of insertion, gestational age, birth weight, and catheter type.
Implications For Practice And Research:
In parallel with currently published international literature, this study's findings support catheter securement with an octyl-based tissue adhesive in use with central venous catheters. When device stabilization is most pertinent, securement with tissue adhesive is a safe and effective method for long-term vascular access among the neonatal population.
