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Related Experiment Video

Updated: Oct 14, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

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[Current approaches to targeted prostate biopsy].

S V Popov1,2,3,4, I N Orlov1,2,3,4, S M Malevich1,2,3,4

  • 1SPb GBUZ City Hospital Saint Luka, Saint Petersburg, Russia.

Urologiia (Moscow, Russia : 1999)
|November 7, 2021
PubMed
Summary

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Multiparametric MRI-guided targeted prostate biopsy improves cancer detection and accuracy. This method enhances diagnosis of clinically significant prostate cancer (PCa) while reducing low-risk tumor identification.

Area of Science:

  • Urology
  • Oncology
  • Radiology

Background:

  • Prostate cancer (PCa) is a leading cause of cancer death in men, with increasing incidence and mortality.
  • Traditional systematic transrectal biopsy has limitations impacting diagnostic accuracy for PCa.
  • Accurate staging is crucial for effective PCa management and patient selection for treatments like active surveillance.

Purpose of the Study:

  • To review optimal approaches for MRI-guided targeted prostate biopsy.
  • To evaluate the potential of multiparametric MRI (mpMRI) in the primary diagnostic algorithm for PCa.
  • To highlight the benefits of MRI-guided biopsy for improving PCa detection and management.

Main Methods:

  • Review of large-scale studies on targeted prostate biopsy techniques.
Keywords:
Fusion-biopsyMRIdiagnosis of the prostate cancerprostate cancertargeted biopsy

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Last Updated: Oct 14, 2025

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  • Analysis of the integration of multiparametric MRI into the initial diagnostic pathway.
  • Focus on MRI-guided biopsy for sampling suspicious prostate lesions.

    • Main Results:

    • MRI-guided targeted biopsy significantly increases overall PCa detection rates.
    • This technique enhances the detection of clinically significant prostate cancer (csPCa).
    • It reduces the diagnosis of low-risk tumors and improves overall diagnostic accuracy.

    Conclusions:

    • Multiparametric MRI-guided targeted biopsy is the most accurate method for tissue sampling in suspicious areas.
    • Incorporating mpMRI into the primary diagnostic algorithm improves PCa detection and staging.
    • Accurate detection is vital for appropriate patient selection for active surveillance and monitoring disease progression.