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CONCURRENT DEEP VEIN THROMBOSIS AND PULMONARY EMBOLISM ASSOCIATED WITH HYPERTHYROIDISM: A CASE REPORT
Josip Katić1, Ana Katić1, Karla Katić1
11Department of Cardiology, Split University Hospital Centre, Split, Croatia; 2University of Split School of Medicine, Split, Croatia; 3Department of Ophthalmology, Split University Hospital Centre, Split, Croatia.
Acta Clinica Croatica
|November 8, 2021
Summary
Hyperthyroidism increases the risk of pulmonary embolism, a serious condition. Thyroid evaluation is crucial for patients experiencing unprovoked venous thromboembolic events.
Area of Science:
- Endocrinology
- Hematology
- Cardiovascular Medicine
Background:
- Thyroid disorders, particularly hyperthyroidism, are linked to coagulation and fibrinolysis abnormalities.
- Research predominantly focuses on deep vein thrombosis risk, with limited data on pulmonary embolism association.
Observation:
- A case study of a 43-year-old woman with uncontrolled hyperthyroidism presented with venous thromboembolism.
- This highlights a potential complication of hyperthyroidism that is often overlooked.
Findings:
- Hyperthyroidism may contribute to pulmonary embolism through endothelial dysfunction.
- Decreased fibrinolytic activity and elevated coagulation factors are potential underlying mechanisms.
- The case suggests a direct link between hyperthyroidism and thromboembolic events.
Implications:
- Clinicians should consider thyroid dysfunction in patients with unexplained venous thromboembolic events.
- Routine thyroid evaluation may be warranted for individuals with unprovoked pulmonary embolism.
- Further research is needed to elucidate the precise mechanisms linking hyperthyroidism and thromboembolism.
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