Related Experiment Video
Updated: Oct 14, 2025

Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
Published on: July 11, 2025
Sequenced Breakpoints of Crossover Suppressor/Inversion qC1
Mark L Edgley1, Stephane Flibotte2, Donald G Moerman1
1Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada.
Abstract:
We used whole-genome sequencing (WGS) data from a number of balanced lethal strains in Caenorhabditis elegans to show that the crossover suppressor qC1 is an inversion. The rearrangement is complex, with a large primary inversion that contains several other smaller inverted regions. The graphical representation below depicts these various qC1 rearrangements for ease of conceptualization. It is the simplest chromosomal structure compatible with the data currently available, but even then it is worth noting that the complexity of the qC1 chromosome can make the graphical reconstruction difficult to understand, and it may seem a bit like relativity theory or artwork from M.C. Escher (https://moa.byu.edu/m-c-eschers-relativity/).
More Related Videos
Related Concept Videos
Gene Conversion
Crossing Over
Restarting Stalled Replication Forks
Long-patch Base Excision Repair
Conservative Site-specific Recombination and Phase Variation
The recognition sites for Cre recombinase called LoxP...
Homologous Recombination

