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Related Concept Videos

Sample Handling01:02

Sample Handling

174
Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...
174

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BioSamples database: FAIRer samples metadata to accelerate research data management.

Mélanie Courtot1, Dipayan Gupta1, Isuru Liyanage1

  • 1European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK.

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Summary
This summary is machine-generated.

The EMBL-EBI BioSamples database enhances sample data quality and accessibility through technical improvements. It supports diverse research, including plant genomics and COVID-19 multi-omics, by enriching metadata and adhering to FAIR principles.

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Area of Science:

  • Bioinformatics
  • Data Management
  • Genomics

Background:

  • The EMBL-EBI BioSamples database is a central repository for sample metadata.
  • Recent infrastructure upgrades have enabled scalability to accommodate more users and heterogeneous data.
  • There is an increasing need for improved data quality and FAIR (Findable, Accessible, Interoperable, Reusable) principles in biological sample data.

Purpose of the Study:

  • To describe the features and processes implemented in BioSamples in 2021 to improve data quality and metadata enrichment.
  • To showcase exemplar use cases demonstrating how BioSamples supports user requirements and research goals.
  • To highlight the contribution of BioSamples improvements to multi-omics data integration and broader community engagement.

Main Methods:

  • Technical infrastructure improvements to enhance scalability and data handling.
  • Implementation of features and processes for metadata enrichment and data quality control.
  • Development of use cases illustrating support for projects like ReSOLUTE, plant genomics, and COVID-19 research.

Main Results:

  • Increased findability of samples and improved data management practices.
  • Enhanced ability to link genotypic to phenotypic information for the plant community.
  • Facilitation of complex multi-omics data integration, particularly for COVID-19 research.

Conclusions:

  • BioSamples has evolved to meet diverse user needs through enhanced features and processes.
  • The database plays a crucial role in advancing multi-omics research and adhering to FAIR principles.
  • Continuous technical development supports expanded engagement with scientific communities and data integration efforts.