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Updated: Oct 14, 2025

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Optical coherence tomography (OCT) angiolytics: a review of OCT angiography quantitative biomarkers
Gagan Kalra1, Javier Zarranz-Ventura2, Rutvi Chahal3
1Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA; Government Medical College and Hospital, Chandigarh, India.
Abstract:
Optical coherence tomography angiography (OCTA) provides a non-invasive method to obtain angiography of the chorioretinal vasculature leading to its recent widespread adoption. With a growing number of studies exploring the use of OCTA, various biomarkers quantifying the vascular characteristics have come to light. In the current report, we summarize the biomarkers currently described for retinal and choroidal vasculature using OCTA systems and the methods used to obtain them. Further, we present a critical review of these methods and key findings in common retinal diseases and appraise future directions, including applications of artificial intelligence in OCTA .

