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Updated: Oct 14, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Covid-19 pneumonia: An unusual radiological presentation
Anuj Kumar1, Surabhi Jaggi1, Siddarth Singh1
1Department of Pulmonary Medicine, GMCH, Sector 32, Chandigarh, India.
A 26-year-old female initially tested negative for COVID-19 but later showed positive results. She improved with standard COVID-19 treatment, highlighting the importance of further testing for severe respiratory illness.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- This case highlights a diagnostic challenge in a young adult presenting with symptoms suggestive of pneumonia.
- Initial negative nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Real-Time Polymerase Chain Reaction (RT-PCR) complicated the early assessment.
Observation:
- The patient presented with high-grade fever and cough, exhibiting bronchial breathing and rhonchi on examination.
- Chest X-ray revealed left lower zone consolidation, while High-Resolution Computed Tomography (HRCT) demonstrated consolidation with ground-glass opacities (GGO) and a cavitary lesion in the left lower lobe.
Findings:
- Sputum RT-PCR for SARS-CoV-2, the virus causing COVID-19, was positive, confirming the diagnosis despite the initial negative swab.
- The patient received management according to the established COVID-19 protocol.
Implications:
- This case underscores the potential for false-negative results in initial COVID-19 testing, particularly with nasopharyngeal swabs.
- It emphasizes the utility of advanced imaging like HRCT and sputum analysis in diagnosing complex COVID-19 cases with pulmonary involvement.
- Prompt diagnosis and adherence to COVID-19 protocols led to favorable clinical and radiological recovery.
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