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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Skin Cancer01:30

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
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Reticular Dermis01:15

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Related Experiment Video

Updated: Oct 13, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

264

Dermoscopy in cutaneous sarcoidosis.

Agnes Yeok Loo Lim, Po Yin Tang, Choon Chiat Oh1

  • 1Department of Dermatology, Singapore General Hospital. oh.choon.chiat@singhealth.com.sg.

Dermatology Online Journal
|November 10, 2021
PubMed
Summary

Dermoscopy revealed unusual shiny white lines and orange globules in a patient with cutaneous sarcoidosis, aiding clinical diagnosis. This case expands the known dermoscopic findings for sarcoidosis, offering new diagnostic insights.

Area of Science:

  • Dermatology
  • Pathology
  • Medical Imaging

Background:

  • Cutaneous sarcoidosis presents diverse clinical manifestations, often complicating diagnosis.
  • Dermoscopy serves as a valuable non-invasive tool for supporting clinical assessments in dermatology.
  • Accurate diagnosis is crucial for effective management of cutaneous sarcoidosis.

Observation:

  • An elderly female presented with itchy facial plaques suggestive of a skin condition.
  • Dermoscopic examination revealed characteristic translucent orange globules and previously unreported shiny white lines.
  • Histopathological analysis confirmed non-necrotizing granulomas with perigranulomatous fibrosis.

Findings:

  • The presence of shiny white structures on dermoscopy, typically linked to basal cell carcinoma, melanoma, or dermatofibroma, was observed in a confirmed sarcoidosis case.

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  • This finding expands the spectrum of dermoscopic features associated with cutaneous sarcoidosis.
  • The study correlates specific dermoscopic patterns with histopathological findings of sarcoidosis.

    • Implications:

    • This case broadens the differential diagnosis for lesions exhibiting shiny white structures on dermoscopy.
    • Enhanced understanding of dermoscopic findings can improve early and accurate diagnosis of cutaneous sarcoidosis.
    • The report encourages further research into dermoscopy's role in diagnosing various cutaneous conditions.