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Refractory hypoglycemia induced by a duodenal wall gastrointestinal stromal tumor: A case report
Foolad Eghbali1,2, Reza Karami1
1Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran.
Background:
Tumor-associated hypoglycemia can be caused by non-islet cell tumors including gastrointestinal stromal tumor (GIST) which is a rare paraneoplastic syndrome that leads to the release of insulin-like growth factor-2 (IGF-2).
Case Presentation:
We report the case of a 45-year old woman who was admitted to our hospital with refractory hypoglycemic episodes. We found normal serum insulin and c-peptide level and abdominal CT-scan showed a small duodenal wall lesion suggesting insulinoma. After tumor resection, hypoglycemia symptoms were recovered, but the pathological findings demonstrated the lesion was GIST.
Conclusion:
In a small gastrointestinal lesion with hypoglycemic symptoms we should consider IGF-II secreting GIST in addition to insulinoma.
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