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Updated: Oct 13, 2025
Performing In Vivo and Ex Vivo Electrical Impedance Myography in Rodents
Published on: June 8, 2022
Interrater and Intrarater Reliability of Electrical Impedance Myography: A Comparison between Large and Small
Huijing Hu1, Wai Leung Ambrose Lo2, Xiaoyun Wang3
1Institute of Medical Research, Northwestern Polytechnical University, Xi'an 710072, Shaanxi, China.
Abstract:
The objective of this study was to evaluate the interrater and intrarater reliability of electrical impedance myography (EIM) using handheld sensors of different sizes. Electrical impedance myography of the biceps brachii muscle of twenty healthy individuals was performed by two raters using both large and small sensors. The procedures were also repeated 5 to 8 days after the first recording session. The repeatability of the resistance, reactance, and phase angle at two different current frequencies (50 and 100 kHz) was assessed by the intraclass correlation coefficient (ICC). The ICCs of the large sensor were higher than those of the small sensor for both the intrarater and interrater reliabilities. High-frequency current tended to improve the ICC for the small sensor. These results indicate reasonable repeatability of the handheld electrode arrays for EIM measurements. The findings suggest that electrode array should be selected appropriately according to the size of the tested muscle.
