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Printability-A key issue in extrusion-based bioprinting.

Saman Naghieh1, Xiongbiao Chen1,2

  • 1Division of Biomedical Engineering, College of Engineering, University of Saskatchewan, Saskatoon, SK, S7N 5A9, Canada.

Journal of Pharmaceutical Analysis
|November 12, 2021
PubMed
Summary
This summary is machine-generated.

Printability is crucial for 3D extrusion-based bioprinting of scaffolds. This review defines printability, discusses assessment methods, and identifies factors affecting it for improved tissue engineering constructs.

Keywords:
3D bioprintingBioinkExtrusionPrintabilityTissue engineering

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Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Three-dimensional (3D) extrusion-based bioprinting is a key technology in tissue engineering and regenerative medicine.
  • A critical challenge is ensuring the printability of bioinks for creating reproducible cell-incorporated scaffolds.

Purpose of the Study:

  • To review recent advancements in assessing the printability of extrusion-based bioprinting.
  • To define printability, explore measurement techniques, and identify influencing factors.

Main Methods:

  • Literature review focusing on printability assessment in 3D extrusion bioprinting.
  • Analysis of factors affecting bioink and scaffold printability.
  • Identification of challenges and strategies for improving printability.

Main Results:

  • Printability is influenced by bioink properties, printing parameters, and scaffold design.
  • Various methods exist for printability measurement and characterization.
  • Key challenges and potential solutions for enhancing printability were identified.

Conclusions:

  • Improving printability is essential for advancing 3D extrusion-based bioprinting applications.
  • Further research is needed to standardize printability assessment and optimize influencing factors.