Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

4.7K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
4.7K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

5.5K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
5.5K
The Parathyroid Glands00:59

The Parathyroid Glands

2.8K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
2.8K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

10.2K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
10.2K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

3.4K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
3.4K
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

1.9K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assay-dependent discordance in detecting a rare HLA-DPB1 allele: long-range PCR vs. hybrid capture NGS.

Human immunology·2026
Same author

The ternary nanocomposite g-C<sub>3</sub>N<sub>4</sub>/TiO<sub>2</sub>@polyaniline embedded in PVDF based triboelectric nanogenerator for energy harvesting.

Scientific reports·2026
Same author

Manifest Preexcitation-Related Cardiac Dysfunction in the Absence of Tachyarrhythmia: A Systematic Review of Literature.

Journal of cardiovascular electrophysiology·2026
Same author

Where Is the Lactate Coming From? An Unusual Presentation of Persistent Lactic Acidosis.

Cureus·2026
Same author

Bioinformatics analysis of TRPV1 expression and its role in hepatocellular carcinoma prognosis.

Discover oncology·2026
Same author

Revisiting the Intracranial Neurological Imaging Manifestations of Human Immunodeficiency Virus: Pictorial Review with a Pattern-Based Approach.

The Indian journal of radiology & imaging·2026
Same journal

Pleural Toxocariasis Presenting as Eosinophilic Pleural Effusion: A Case Report.

Cureus·2026
Same journal

Left Clavicular Pain Following Splenic Rupture After Colonoscopy: A Variant of Kehr's Sign?

Cureus·2026
Same journal

Severe Polyhydramnios Associated With Antenatal Bartter Syndrome.

Cureus·2026
Same journal

Focal Takotsubo Syndrome Mimicking a Distal Coronary Pathology: A Case Report.

Cureus·2026
Same journal

Metachronous Colorectal Carcinomas and Pancreatic Metastasis in Clinically Suspected Lynch Syndrome: An 18-Year Oncologic Course.

Cureus·2026
Same journal

Regional Blocks in the Era of the Opioid Crisis: Evaluating Their Opioid-Sparing Effect.

Cureus·2026
See all related articles

Related Experiment Video

Updated: Oct 13, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

1.8K

Ectopic Mediastinal and Lumbar Thyroid Tissue.

Salman Khan1, Madeeha Subhan Waleed2, Deepak Verma3

  • 1Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.

Cureus
|November 12, 2021
PubMed
Summary
This summary is machine-generated.

Ectopic thyroid tissue (ETT) is rarely found outside the neck. This report details a case of a 19-year-old female diagnosed with lumbar and posterior mediastinal ETT after thyroid surgery.

Keywords:
: thyroid noduleectopic thyroid tissuelumbarmediastinumthyroglobulinthyroid cancer

More Related Videos

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.3K
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

25.8K

Related Experiment Videos

Last Updated: Oct 13, 2025

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

1.8K
An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.3K
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

25.8K

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Anatomic Pathology

Background:

  • The thyroid gland, typically located in the neck, comprises follicular cells and C cells.
  • Ectopic thyroid tissue (ETT) refers to thyroid tissue found outside its normal anatomical location.
  • ETT can present as a diagnostic challenge due to its varied locations and potential for malignancy.

Observation:

  • A 19-year-old female presented with a large dominant thyroid nodule requiring total thyroidectomy.
  • Post-operatively, the patient was diagnosed with ectopic thyroid tissue (ETT) in both the lumbar and posterior mediastinal regions.
  • This case highlights unusual locations for ETT, emphasizing the need for thorough diagnostic evaluation.

Findings:

  • The patient's ectopic thyroid tissue was confirmed histopathologically in the lumbar and posterior mediastinal sites.
  • The presence of ETT in these locations is rare and suggests developmental anomalies.
  • The diagnosis was made following surgical management for a primary thyroid nodule.

Implications:

  • Physicians must maintain a high index of suspicion for ETT, even in extrathyroidal locations.
  • Prompt and accurate diagnosis of ETT is crucial to prevent complications and guide appropriate management.
  • Understanding the diverse presentations of ETT aids in improving patient outcomes and reducing associated morbidity.