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The Application of Exercise Training for Diabetic Peripheral Neuropathy
Clifton J Holmes1,2, Mary K Hastings1
1Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO 63110, USA.
Journal of Clinical Medicine
|November 13, 2021
Summary
Exercise training shows promise for improving physical fitness and sensorimotor function in individuals with diabetic peripheral neuropathy (DPN). This review discusses exercise effects on DPN, aiding future recommendations.
Area of Science:
- Neurology
- Endocrinology
- Sports Medicine
Background:
- Diabetic peripheral neuropathy (DPN) involves nerve dysfunction in people with diabetes, leading to pain, sensory loss, and muscle atrophy.
- DPN can cause reduced mobility, increasing risks of disability, ulceration, and amputation.
- Exercise training is known to improve physical fitness, body composition, and neuromuscular strength.
Purpose of the Study:
- To review the pathophysiology of DPN.
- To discuss the impact of exercise interventions on sensorimotor, metabolic, and physical functions in DPN patients.
Main Methods:
- Literature review of experimental studies on exercise training for DPN.
- Analysis of various exercise modalities and outcome measurements.
Main Results:
- Exercise training has been explored for improving nerve conduction velocity, pain tolerance, and balance in DPN.
- Varied exercise approaches and outcome measures complicate definitive efficacy assessment.
Conclusions:
- Exercise training interventions present potential benefits for individuals with DPN.
- Further research is needed to establish optimal exercise prescriptions for managing DPN.
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