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Deep Vision for Breast Cancer Classification and Segmentation.

Lawrence Fulton1, Alex McLeod2, Diane Dolezel3

  • 1College of Health Professions, Texas State University, San Marcos, TX 78666, USA.

Cancers
|November 13, 2021
PubMed
Summary

Deep vision AI accurately classifies mammograms, potentially reducing overdiagnosis and improving early detection of breast cancer. This technology aids in identifying critical regions, supporting clinicians and enhancing diagnostic accuracy.

Keywords:
breast cancerdeep visionmachine learningregion of interest detection

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Area of Science:

  • Artificial Intelligence in Medical Imaging
  • Deep Learning for Diagnostic Support
  • Mammography Image Analysis

Background:

  • Rising breast cancer diagnosis rates necessitate improved screening accuracy.
  • High false positive rates (FPR) in mammography lead to overdiagnosis and overtreatment.
  • False negative rates (FNR) contribute to increased patient morbidity and mortality.

Purpose of the Study:

  • To develop and evaluate a deep vision supervised learning model for mammography classification.
  • To assess the model's accuracy, specificity, and sensitivity in detecting breast cancer.
  • To explore gradient-based techniques for automated region of interest (ROI) identification.

Main Methods:

  • Supervised learning models trained on 55,890 de-noised mammography images (299x299 pixels).
  • Application of trained models to a test set of 15,364 unseen images for classification.
  • Utilizing loss function gradients to identify image regions crucial for classification decisions.

Main Results:

  • Achieved 97% accuracy, 99% specificity, and 83% sensitivity in initial classification.
  • Gradient techniques successfully mapped influential regions on positive mammograms.
  • Demonstrated potential for supporting clinical analysis through automated ROI identification.

Conclusions:

  • Deep vision techniques show promise in mitigating mammography overdiagnosis and underdiagnosis.
  • Automated ROI identification can assist clinicians in mammogram interpretation.
  • AI-powered analysis offers a pathway to more accurate and efficient breast cancer screening.