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Updated: Oct 13, 2025

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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
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Evaluation of the vitreolenticular interface with intraoperative OCT
Arnout Vael1, Luc Van Os, Kirsten Melis
1From the Department of Ophthalmology, University Hospital Antwerp, Antwerp, Belgium (Vael, Van Os, Tassignon); Independent Researcher, Antwerp, Belgium (Melis).
Journal of Cataract and Refractive Surgery
|November 14, 2021
Summary
Anterior vitreous detachment (AVD) affects 63% of routine bag-in-the-lens cataract surgery patients, with age being a significant risk factor. This finding aids in preoperative and postoperative assessments.
Area of Science:
- Ophthalmology
- Ophthalmic Surgery
Background:
- Anterior vitreous detachment (AVD) is a common condition.
- Understanding its prevalence in specific surgical contexts is crucial for patient care.
Purpose of the Study:
- To determine the prevalence of anterior vitreous detachment (AVD) in routine bag-in-the-lens (BIL) cataract surgery.
- To identify potential risk factors associated with AVD in this patient group.
Main Methods:
- A prospective cross-sectional study included 99 patients undergoing routine BIL cataract surgery.
- Exclusion criteria included traumatic cataracts, prior intraocular surgeries, and specific medical conditions.
- Data were collected from patient records, surgical videos, photographs, and optical coherence tomography.
Main Results:
- Anterior vitreous detachment (AVD) was observed in 63% of the eyes studied (62 out of 99).
- Age was found to be a statistically significant risk factor for AVD (P < .005).
- The odds of AVD increased by 5.3% for each year of patient age.
Conclusions:
- The prevalence of AVD in routine cataract surgery patients is 63%.
- Increasing age is a confirmed risk factor for AVD.
- Bag-in-the-lens surgery did not increase the risk of posterior segment ocular complications.

