Related Experiment Video
Updated: Oct 13, 2025

Tracking Individual Running Metrics in Mice Using a Voluntary Wheel Running Protocol that Minimizes Social Isolation
Published on: April 18, 2025
Physical activity during the SARS-CoV-2 pandemic is linked to better mood and emotion
Melissa M Markofski1, Kristofer Jennings2, Charles F Hodgman1
1Department of Health and Human Performance, University of Houston, Houston, Texas, USA.
Abstract:
The SARS-CoV-2 pandemic may negatively impact mood and emotion. Physical activity may protect against mood disturbance and promote positive affect. This study asked if physical activity before, during, or the change in physical activity with the pandemic, impacted affect and mood during the pandemic. US adult residents (18-74 years; N = 338) were surveyed from 29 April to 3 June 2020. Physical activity before and during the pandemic was assessed with the Physical Activity Rating survey. The Positive and Negative Affect Schedule measured affect and the Profile of Moods Questionnaire assessed mood. Comparisons between physically inactive and active participants by Analysis of Covariance found greater vigour in participants classed as physically active before the pandemic. Positive affect, vigour and esteem-related affect were greater in participants physically active during the pandemic. Multiple linear regression revealed relationships between the change in physical activity and mood. Change in physical activity positively associated with positive affect (b = 1.06), esteem-related affect (b = 0.33) and vigour (b = 0.53), and negatively associated with negative affect (b = -0.47), total mood disturbance (b = -2.60), tension (b = -0.31), anger (b = -0.24), fatigue (b = -0.54), depression (b = -0.50) and confusion (b = -0.23). These data demonstrate that physical activity during the pandemic, and increased physical activity relative to before the pandemic, related to better mood.
Related Concept Videos
Coping Strategies: Emotion Focused
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Social Relationships and Well-Being
Introduction to Stress and Lifestyle
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Physiology of Emotion
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...

