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Toxicity of imipenem in vitreous replacement fluid
R J Derick1, R Paylor, G A Peyman
1Department of Ophthalmology, Eye and Ear Infirmary, University of Illinois College of Medicine, Chicago.
Abstract:
We evaluated the ocular toxicity of imipenem when administered in the infusion fluid during vitrectomy. Imipenem concentrations of up to 16 micrograms/mL were nontoxic to the ocular structures.