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Pathways and Pathogenesis of Hearing Deficits, Tinnitus, and Vertigo in COVID-19
1Department of Biological and Biomedical Sciences, Aga Khan University, Karachi 78400, Pakistan.
Abstract:
COVID-19 has been shown to affect the ear and has led to hearing deficits, tinnitus, and vertigo. Very little is known regarding the mechanisms and targets of SARS-CoV-2 that cause the above symptoms. Anatomical extensions from the areas of viral loads to the middle ear appear to enable the SARS-CoV-2 to cause either an inflammatory response or a direct effect on the lining epithelium leading to temporary hearing and equilibrium-related symptoms in COVID-19. Herein the anatomical continuity from the areas of viral loads to the middle and internal ear is debated to uncover the possible covert routes used by SARS-CoV-2 to affect the hearing and equilibrium in COVID-19.
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