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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
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Hydroxyapatite, a potent agent to reduce dentin hypersensitivity.

Hashmat Gul1, Muhammad Asad Ghaffar1, Muhammad Kaleem1

  • 1Department of Dental Materials, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan.

JPMA. the Journal of the Pakistan Medical Association
|November 16, 2021
PubMed
Summary
This summary is machine-generated.

Hydroxyapatite effectively treats dentin hypersensitivity by blocking dentinal tubules. This review confirms its potential for reducing tooth sensitivity within weeks.

Keywords:
Dentin hypersensitivity, Hydroxyapatite, Dentinal tubule occlusion.

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Area of Science:

  • Biomaterials Science
  • Dental Research
  • Nanotechnology

Background:

  • Dentin hypersensitivity is a common dental condition characterized by sharp pain.
  • It arises from exposed dentinal tubules, allowing stimuli to reach the nerve.
  • Current treatments aim to occlude these tubules to reduce sensitivity.

Approach:

  • A systematic literature review was conducted.
  • Searched PubMed, Science Direct, and Web of Science databases for articles published between 2009 and 2018.
  • Included studies focused on hydroxyapatite application for dentin hypersensitivity and dentinal tubule occlusion.

Key Points:

  • Hydroxyapatite application leads to dentinal tubule occlusion.
  • Occlusion of dentinal tubules reduces dentin permeability.
  • Reduced dentin permeability correlates with decreased dentin hypersensitivity.

Conclusions:

  • Hydroxyapatite shows significant potential as a treatment for dentin hypersensitivity.
  • Application of hydroxyapatite facilitates dentinal tubule occlusion, reducing tooth sensitivity.
  • Visible results for reduced dentin hypersensitivity were observed within 2-8 weeks.