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[Innovations in peritoneal dialysis]
R Hausinger1, C Schmaderer1, U Heemann1
1Abteilung für Nephrologie, Klinikum rechts der Isar, Technische Universität München, Ismaningerstr. 22, 81675 München, Deutschland.
Der Nephrologe
|November 17, 2021
Summary
Peritoneal dialysis is resurging for acute kidney failure due to its simplicity and low resource needs, especially after the COVID-19 pandemic. Future innovations like wearable artificial kidneys and dialysate regeneration promise further advancements.
Area of Science:
- Nephrology
- Biomedical Engineering
Context:
- Peritoneal dialysis (PD) was historically common for acute kidney failure but declined in Western countries.
- It remains vital in resource-limited regions due to simplicity and low cost.
- The COVID-19 pandemic revived global interest in PD as a safe acute dialysis option.
Purpose:
- To review the current status and future prospects of peritoneal dialysis.
- To highlight recent advancements and potential innovations in PD therapy.
Summary:
- Biocompatible solutions introduced 20 years ago aimed to reduce PD complications, though evidence remains limited.
- Immunomodulatory adjuvants offer potential for improved local immunity and prevention of peritoneal function loss.
- Wearable artificial kidney technology and intensified dialysis with minimal dialysate volumes are emerging possibilities.
Impact:
- PD offers a sustainable dialysis option, with dialysate regeneration potentially conserving water and reducing CO2 emissions.
- Innovations may enhance PD efficacy and patient outcomes, making it a more viable treatment globally.
- The resurgence of PD reflects its adaptability and potential to address healthcare challenges, including resource limitations and pandemics.
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