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Published on: November 7, 2020
[Covid-19 respiratory sequelae : Screening and management].
Minh Khoa Truong1, Georgia Mitropoulou1, Alexandra Lenoir1
1Service de pneumologie, Département de médecine, Centre hospitalier universitaire vaudois, CHUV, et Université de Lausanne, 1011 Lausanne.
Severe COVID-19 (SARS-CoV-2) can impair lung function and exercise capacity for months. Pulmonary rehabilitation is key for recovery, but specific therapies require further evaluation.
Area of Science:
- Respiratory Medicine
- Infectious Diseases
- Pulmonology
Background:
- SARS-CoV-2 infection frequently impacts the respiratory system, leading to persistent symptoms and reduced lung function.
- Post-acute sequelae of COVID-19 include diminished exercise capacity and chest CT anomalies.
- Established guidelines address the post-acute care of SARS-CoV-2 patients.
Purpose of the Study:
- To summarize current understanding of post-acute respiratory consequences of SARS-CoV-2 infection.
- To highlight the role of pulmonary rehabilitation in recovery.
- To discuss the uncertain role of specific therapeutic interventions.
Main Methods:
- Review of current literature and clinical guidelines on post-COVID-19 respiratory care.
- Analysis of the impact of SARS-CoV-2 on lung function and exercise capacity.
- Evaluation of the evidence for specific therapies in post-acute management.
Main Results:
- Persistent respiratory symptoms and reduced lung function are common after SARS-CoV-2 infection.
- Pulmonary rehabilitation is crucial for improving exercise capacity, especially in severe cases.
- The efficacy of corticosteroids, anti-fibrotics, and lung transplantation is not yet established.
Conclusions:
- Pulmonary rehabilitation is a cornerstone of post-acute SARS-CoV-2 respiratory care.
- Individualized assessment is necessary for specific therapies like corticosteroids and anti-fibrotics.
- Further research is needed to clarify the role of advanced interventions such as lung transplantation.
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