Related Experiment Video
Updated: Oct 13, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Percutaneous Closure of Paravalvular Regurgitation After Third-Generation Transcatheter Aortic Valve Replacement
Eustaquio Maria Onorato1, Matteo Vercellino2, Anna Maria Costante3
1Centro Cardiologico Monzino, IRCCS University School of Milan.
Abstract:
Significant paravalvular leak regurgitation (PVLR) after transcatheter aortic valve replacement (TAVR) is a well-known complication associated with disabling symptoms related to heart failure and hemolysis or both, with poor prognostic implications. Although challenging and technically demanding, percutaneous closure is an effective treatment option for high-risk patients with symptomatic PVLR. Here, we present two cases of transcatheter PVLR closure after replacement of third-generation (one self-expandable and one balloon-expandable) transcatheter aortic valves, each with peculiar challenges, and the strategies adopted to increase the success rate of percutaneous closure.
Related Concept Videos
Aortic Regurgitation III: Medical Management
Mitral Regurgitation III: Medical Management
Mitral Stenosis III: Medical Management
Aneurysm III: Interprofessional Care
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation IV: Nursing Management

