Shape-factor intensity analyses of brain slices in surgery for epilepsy

A special shape-factor intensity (SFI) quantification method for analysing of macro- and microrecordings of brain activity during surgery for epilepsy is illustrated. Comparative analyses show that epileptic activity may be characterized as different from normal brain activity by both macro-and microtechniques. The possible advantages of brain slice technique in comparison with direct peroperative microrecording are discussed; absence of artifacts from respiratory and pulsatory movements of the brain is stressed. The slice technique cannot be advocated for routine use in epilepsy surgery as it requires advanced neurophysiological knowledge.