Platypnoea-Orthodeoxia Syndrome in COVID-19

Area of Science:

• Medicine
• Pulmonology
• Infectious Diseases

Background:

• Platypnoea-orthodeoxia syndrome (POS) is a rare disorder with poorly understood pathophysiology.
• Limited literature describes POS in COVID-19 patients, with varied associated conditions.

Purpose of the Study:

• To report a case of POS developing during hospitalization in a patient with SARS-CoV-2 interstitial pneumonia.
• To highlight the importance of recognizing POS in the context of COVID-19.

Main Methods:

• Case report of a hospitalized patient with SARS-CoV-2 interstitial pneumonia.
• Clinical observation and diagnosis of POS during the course of hospitalization.

Main Results:

• The patient with SARS-CoV-2 pneumonia developed Platypnoea-orthodeoxia syndrome.
• This case adds to the limited understanding of POS in COVID-19 patients.

Conclusions:

• Platypnoea-orthodeoxia syndrome is a rare but possible complication of SARS-CoV-2 pneumonia.
• Early diagnosis and appropriate oxygen management are vital for patients with POS.
• Further clinical data on COVID-19 evolution and management strategies for POS patients are needed.