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COVID-19 vaccines for children

Jeffrey S Gerber1, Paul A Offit2

  • 1Jeffrey S. Gerber is an associate professor of Pediatrics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA and deputy director of the Center for Pediatric Clinical Effectiveness at Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Science (New York, N.Y.)
|November 18, 2021
PubMed

Insights

Pfizer

Area of Science:

  • Pediatric infectious diseases
  • Vaccinology
  • Public health

Background:

  • The US CDC recommends Pfizer's COVID-19 mRNA vaccine for 28 million children aged 5-11.
  • Parental vaccine hesitancy is high, with 42-66% reluctant or opposed.
  • Widespread natural infection with SARS-CoV-2 is probable for all, including children.

Discussion:

  • Comparing the risks of COVID-19 vaccination versus natural SARS-CoV-2 infection in children.
  • Addressing parental concerns regarding pediatric COVID-19 vaccination.
  • Evaluating the long-term health implications of childhood COVID-19 infection.

Key Insights:

  • The dilemma for parents: choosing between vaccination and natural infection for their children.
  • Understanding the comparative safety and efficacy profiles of vaccines and natural immunity.
  • The critical need for clear, evidence-based information to guide parental decisions.

Outlook:

  • Potential strategies to increase pediatric COVID-19 vaccine uptake.
  • Ongoing research into the long-term effects of COVID-19 in children.
  • The role of vaccination in mitigating the impact of SARS-CoV-2 on pediatric populations.

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