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Updated: Oct 13, 2025
Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
Published on: April 14, 2023
Strategic Planning and Essential Steps for Establishing a Uterine Transplant and Rehabilitation Program: From Idea to
Amir H Dorafshar1, Alireza Hamidian Jahromi1, Sydney R Horen1
1Division of Plastic & Reconstructive Surgery, Rush University Medical Center, Chicago, IL.
Abstract:
UTx is performed to address absolute uterine infertility in the presence of uterine agenesis, a nonfunctional uterus, or after a prior hysterectomy. After the initial success of UTx resulting in a livebirth (2014) in Sweden, there are over 70 reported UTx surgeries resulting in more than 40 livebirths worldwide. Currently, UTx has been performed in over 10 countries. As UTx is transitioning from an "experimental procedure" to a clinical option, an increasing number of centers may contemplate a UTx program. This article discusses essential steps for establishment of a successful UTx program. These principles may be implemented in cis- and transgender UTx candidates.
