[Use of ofloxacin in otorhinolaryngologic infections]

Ofloxacin, a new fluoroquinolonic synthetic compound with broad antibacterial spectrum, was used in per os therapy of 15 ear, nose and throat infected patients. The antibiotic was then compared with other eight antimicrobial agents against the Gram-positive and Gram-negative isolates. Either in vitro than in vivo the god antibacterial activity and tolerance of ofloxacin, particularly against Gram-positive infections, was demonstrated. Results point out the possibility of utilization of ofloxacin per os against ear, nose and throat infections.