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Updated: Oct 12, 2025

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
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Cross-Linking Mass Spectrometry for Investigating Protein Conformations and Protein-Protein Interactions─A Method for

Lolita Piersimoni1,2, Panagiotis L Kastritis3,4,5, Christian Arlt1,2

  • 1Department of Pharmaceutical Chemistry & Bioanalytics, Institute of Pharmacy, Kurt-Mothes-Strasse 3, D-06120 Halle (Saale), Germany.

Chemical Reviews
|November 19, 2021
PubMed

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