Related Experiment Video
Updated: Oct 12, 2025

08:29
Using Coculture to Detect Chemically Mediated Interspecies Interactions
Published on: October 31, 2013
13.7K
Sweet sensation: Developing a single-cell fluorescent reporter of glycolytic heterogeneity
Diane B Karloff1, Jennifer M Heemstra2
1Department of Chemistry, Emory University, Atlanta, GA 30322, USA.
Cell Chemical Biology
|November 19, 2021
Abstract:
Conversion of in vitro selected aptamers into functional metabolic sensors is hampered by reduced in vivo aptamer binding and limited tunability of cellular metabolite levels. In this issue of Cell Chemical Biology, Ortega et al. (2021) construct RNA sensors of fructose-6-bisphosphate (FBP) that report on metabolite levels within single yeast cells.

