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Updated: Oct 12, 2025

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Diagnosis and Management of Central Nervous System Demyelinating Disorders
Lahoud Touma1, Alexandra Muccilli2
1Department of Neurosciences, Unviersity of Montreal, Centre Hospitalier de l'Université de Montréal.
Abstract:
The spectrum of demyelinating diseases affecting the central nervous system is broad. Although many have a chronic course, neuroinflammatory conditions often present with acute to subacute onset symptoms requiring hospitalization when severe. This article reviews the acute phase assessment and management of these disorders, with a particular focus on multiple sclerosis, neuromyelitis optica spectrum disorder, myelin oligodendrocyte glycoprotein antibody disorder, and several atypical demyelinating diseases.
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