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Randomized crossover study comparing quantitative fit tests between Trident™ and 3M™ Aura™ N95/P2 respirators.

D L Williams1, B Kave2, F Begg3

  • 1University of Melbourne, Parkville, Victoria, 3050, Australia; Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Parkville, Victoria, 3050, Australia.

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Summary

The new Trident P2 respirator showed significantly higher fit test pass rates than the 3M Aura N95 respirator. This study highlights the importance of selecting high-performing filtering facepiece respirators for healthcare worker safety.

Keywords:
Filtering facepiece respiratorQuantitative fit testRespiratory protection equipmentThree-panel flat-fold N95/P2 respirator

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Area of Science:

  • Occupational Health
  • Respiratory Protection
  • Infectious Disease Control

Background:

  • Healthcare workers (HCWs) utilized various N95/P2 filtering facepiece respirators (FFRs) during the COVID-19 pandemic, influenced by national stockpile availability.
  • Previous studies indicate three-panel flat-fold N95/P2 FFRs achieve higher quantitative fit test (QNFT) pass rates compared to other styles.

Purpose of the Study:

  • To prospectively evaluate the performance of the new Trident P2 respirator, a three-panel flat-fold FFR.
  • To compare the Trident P2 respirator against the 3M Aura 9320A+ N95 respirator, a previously effective model, using QNFT.

Main Methods:

  • A prospective randomized crossover study involving 500 participants who completed online training and QNFT on both respirators.
  • The primary outcome was the QNFT pass rate, with secondary outcomes including overall and individual fit factors and first-attempt QNFT pass rates.

Main Results:

  • The Trident P2 respirator demonstrated significantly higher overall QNFT pass rates (99.2%) compared to the 3M Aura (92.6%, p < 0.001).
  • First-attempt QNFT pass rates were also significantly higher for the Trident P2 (92.6%) versus the 3M Aura (76.4%, p < 0.001).
  • Both overall and individual fit factors were significantly superior for the Trident FFR.

Conclusions:

  • This study provides the first hospital-based QNFT results for the Trident FFR, showing very high first-time and overall pass rates.
  • Findings align with prior research on the effectiveness of three-panel flat-fold FFRs.
  • Results are crucial for pandemic preparedness, informing N95/P2 respirator stockpiling and safe usage strategies.