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Updated: Oct 12, 2025
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Recurrent Macroprolactinoma with Malignant Conversion to Carcinoma with Spinal Metastasis
Madeline Mori1, Amanda Frugoli2,3, Udesh Shah2,3
1Western University of Health Sciences, Pomona, CA 91766, USA.
Abstract:
In contrast to pituitary adenomas, pituitary carcinomas represent a rare malignant neoplasm with a remarkable high mortality. Pituitary carcinomas can arise from any pituitary tumor cell line and are determined to be carcinomas when there is distant metastasis or central nervous system dissemination. In this case vignette, we describe a rare case of malignant prolactinoma with intraspinal metastasis, and we also provide a review of relevant literature and treatment.
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