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A LysR-Type Transcriptional Regulator Controls Multiple Phenotypes in Acinetobacter baumannii

Aimee R P Tierney1, Chui Yoke Chin2,3,4,5, David S Weiss2,3,4,5,6

  • 1Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, United States.

Frontiers in Cellular and Infection Microbiology
|November 22, 2021
PubMed
Summary

Acinetobacter baumannii virulence switches between opaque and translucent variants. The gene ABUW_1132 regulates this switch, impacting gene expression, motility, and capsule production, offering a target for virulence attenuation.

Keywords:
AB5075Acinetobacter baumanniiLysR-type transcriptional regulatormotilityphenotypic heterogeneitypolysaccharide capsulequorum sensingvirulence

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