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Updated: Aug 16, 2026

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
Published on: July 25, 2011
Malignant transformation in oral leukoplakia
1Department of Oral Surgery and Oral Medicine, University of Oslo, Norway.
Abstract:
A retrospective study on the incidence of malignant transformation in oral leukoplakia was performed covering the period from 1970 to 1980. Carcinoma developed in 11 of the 157 patients, and this 7% incidence increased to 8.9% when the same patients were followed prospectively for 6 more years. Dysplasia was found in biopsies from 51 patients (31.8%), and was significantly more frequent in women than men (P less than 0.05). Dysplasia grade and cancer development were related to updated clinical and etiological parameters.
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