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Concurrent COVID-19 and dengue with hyperferritinaemia: A case report
1Queen Elizabeth Hospital, Department of Medicine, Kota Kinabalu, Sabah, Malaysia.
Insights
Coinfection with COVID-19 and dengue fever presents diagnostic challenges, especially with hyperferritinaemia. This case highlights the importance of considering both viral infections in endemic tropical regions.
Area of Science:
- Infectious Diseases
- Tropical Medicine
- Clinical Case Reports
Background:
- Coronavirus disease 2019 (COVID-19) pandemic impacts tropical regions with endemic dengue fever.
- Both diseases share overlapping clinical and laboratory features, complicating diagnosis.
- Hyperferritinaemia is linked to severe COVID-19 outcomes and dengue-associated haemophagocytic lymphohistiocytosis (HLH).
Observation:
- A case of coinfection with COVID-19 and dengue fever was observed.
- The patient presented with hyperferritinaemia, a marker of severity in both diseases.
- The case occurred at Queen Elizabeth Hospital in Sabah, Malaysia.
Findings:
- This case report details a coinfection scenario of COVID-19 and dengue.
- Hyperferritinaemia was a significant finding in this coinfection.
- The presentation underscores diagnostic complexities in co-endemic areas.
Implications:
- Highlights the diagnostic challenges of co-occurring COVID-19 and dengue infections.
- Emphasizes the clinical significance of hyperferritinaemia in coinfection.
- Informs clinical management strategies for patients in tropical regions facing dual viral threats.
Abstract:
The current pandemic of coronavirus disease 2019 (COVID- 19) poses a bigger challenge to the population in tropical countries where dengue fever is also endemic as both diseases share similar clinical and laboratory features. In COVID-19, hyperferritinaemia is associated with severe disease and clinical outcome while in dengue fever, hyperferritinaemia is a key feature of haemophagocytic lymphohistiocytosis (HLH), which is a complication with high mortality. In this case report, we present a case of coinfection of COVID-19 and dengue with hyperferritinaemia in Queen Elizabeth Hospital, Sabah, Malaysia.
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