Screening for preterm birth in twin pregnancies

Amanda Roman1, Alexandra Ramirez1, Nathan S Fox2

  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA (Drs Roman and Ramirez).

Twins represent 3.2% of all live births. However, they account for 20% of all preterm deliveries, with 60% delivered before 37 weeks and 10.7% before 32 weeks of gestation. Twin pregnancies have a 5 times higher risk of early neonatal and infant death related to prematurity. Monochorionic twins have a higher incidence of both indicated and spontaneous preterm delivery than dichorionic twins. Additional risk factors include a history of preterm delivery and cervical surgery. The transvaginal cervical length before 24 weeks is the best factor to predict preterm birth, independent of other risk factors.

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