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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

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Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
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Doppler Optical Coherence Tomography of Retinal Circulation
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Doppler Optical Coherence Tomography of Retinal Circulation

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Optical coherence tomography.

Corinna E Psomadakis1, Nadeem Marghoob2, Brady Bleicher3

  • 1Department of Medicine, Mount Sinai West and Morningside, New York, New York, USA.

Clinics in Dermatology
|November 23, 2021
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) provides real-time, noninvasive skin imaging for dermatology. This review covers OCT

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Area of Science:

  • Dermatology and biomedical imaging research.

Background:

  • Noninvasive imaging techniques are increasingly vital in dermatology.
  • Optical coherence tomography (OCT) is a key noninvasive imaging modality.

Purpose of the Study:

  • To review the history, types, and modalities of OCT.
  • To explore the applications of advanced OCT techniques in dermatology.

Main Methods:

  • OCT utilizes interferometry with a low-power diode laser and infrared light.
  • Real-time, two-dimensional cross-sectional images are generated based on light backscattering and time delay.

Main Results:

  • Review of various OCT types including frequency domain, high definition, and dynamic OCT.
  • Demonstration of OCT's utility in diagnosing, monitoring, and grading cutaneous diseases.

Conclusions:

  • Optical coherence tomography is a valuable tool in dermatologic practice and research.
  • OCT facilitates accurate diagnosis and disease management for various skin conditions.