Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

384
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
384
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.0K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.0K
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

4.0K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
4.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FOLR1-targeted actinium-225-based alpha-particle therapy eliminates ovarian cancer.

Science advances·2026
Same author

Pearls and Pitfalls of <sup>18</sup>F-FDG PET/CT for Suspected Alzheimer's Disease in Patient with Down Syndrome.

Molecular imaging and radionuclide therapy·2026
Same authorSame journal

FDG PET in Movement Disorders and Parkinsonian Syndromes.

PET clinics·2026
Same author

Pontine pathology mediates common symptoms of blast-induced chronic mild traumatic brain injury.

Brain communications·2026
Same author

Copathologies of Limbic-Predominant Age-Related TDP-43 Encephalopathy and Alzheimer Disease: [<sup>18</sup>F]FDG PET Statistical Mapping and Quantitative MRI Volumetry.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Real-world experience with lecanemab therapy for Alzheimer's disease in the Intermountain West.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026
Same journal

<sup>18</sup>F-fluorodeoxyglucose PET in Major Psychiatric Disorders.

PET clinics·2026
Same journal

Five Decades of [18F]Fluorodeoxyglucose-PET in Neuropsychiatric Disorders: From Brain Metabolism to Precision Functional Imaging.

PET clinics·2026
Same journal

Brain [18F]FDG PET in Subjective Cognitive Complaints: From Diagnostic Gap to Neurobiological Insight.

PET clinics·2026
Same journal

Brain [18F]FDG PET in Encephalitis and Postinfectious Neurocognitive Syndromes.

PET clinics·2026
Same journal

Theranostics in Nuclear Medicine: Historical, Regulatory, and Evidence Context for the Practicing Nuclear Medicine Physician.

PET clinics·2026
See all related articles

Related Experiment Video

Updated: Oct 12, 2025

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry
08:04

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry

Published on: September 27, 2024

938

Artificial Intelligence for Brain Molecular Imaging.

Donna J Cross1, Seisaku Komori2, Satoshi Minoshima1

  • 1Department of Radiology and Imaging Sciences, University of Utah, 30 North 1900 East #1A71, Salt Lake City, UT 84132-2140, USA.

PET Clinics
|November 23, 2021
PubMed
Summary
This summary is machine-generated.

This article reviews how machine learning and advanced computational models are transforming brain imaging. It explores the history, current uses, and future potential of these tools in medical settings, while emphasizing the ongoing need for human oversight.

Keywords:
Artificial intelligenceBrain molecular imagingDeep learningPETmachine learningmedical diagnosticsneurological scanningpredictive modeling

Frequently Asked Questions

More Related Videos

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol
10:14

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

Published on: May 12, 2019

7.4K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.5K

Related Experiment Videos

Last Updated: Oct 12, 2025

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry
08:04

Molecular Imaging of Human Brain Organoids Using Mass Spectrometry

Published on: September 27, 2024

938
3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol
10:14

3D Scanning Technology Bridging Microcircuits and Macroscale Brain Images in 3D Novel Embedding Overlapping Protocol

Published on: May 12, 2019

7.4K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

10.5K

Area of Science:

  • Artificial Intelligence in medical imaging diagnostics
  • Neuroscience and molecular imaging research

Background:

No prior work had resolved the full trajectory of computational integration within neurological scanning practices. It was already known that automated systems have existed for three decades. That uncertainty drove researchers to examine how recent software advancements changed clinical workflows. Prior research has shown that early efforts focused on basic operational tasks. This gap motivated a comprehensive look at the rapid evolution of these diagnostic technologies. The field has witnessed significant growth over the last twenty years. Scholars have identified a shift toward complex predictive modeling in modern healthcare. This review contextualizes the transition from simple image processing to sophisticated diagnostic support tools.

Purpose Of The Study:

The aim of this review is to evaluate the evolution and clinical impact of computational intelligence within the field of brain molecular imaging. The researchers sought to document how these technologies have progressed from simple operational tasks to complex diagnostic functions. They intended to clarify the role of large data repositories in driving recent software advancements. The study also aimed to address the potential for these systems to achieve superior diagnostic accuracy. Another goal was to examine the necessity of human supervision in the context of increasing software sophistication. The authors wanted to synthesize evidence regarding the current state of these predictive models. They aimed to provide a clear perspective on how these tools influence modern medical practice. This work serves to bridge the gap between historical developments and future expectations in neuroimaging.

Main Methods:

Review Approach involved a systematic synthesis of historical and contemporary literature regarding computational advancements. The investigators examined peer-reviewed publications spanning the last thirty years to track technological progress. They categorized various software applications ranging from basic image reconstruction to complex diagnostic prediction. The team evaluated how the availability of massive data archives influenced current research trends. This synthesis focused on identifying the shift toward multidimensional information processing in clinical settings. The authors assessed the balance between automated software capabilities and the necessity for human intervention. They scrutinized the evolution of these tools to understand their impact on medical practice. The study utilized a qualitative analysis of existing evidence to summarize the field's current state.

Main Results:

Key Findings From the Literature indicate that computational applications have expanded significantly over the past two decades. The authors report that these tools now manage tasks ranging from basic attenuation correction to sophisticated disease prediction. Research shows that the integration of large data repositories has accelerated the development of complex software platforms. The literature suggests that future models will likely incorporate multidimensional datasets to improve diagnostic precision. Evidence demonstrates that these systems are approaching performance levels that may surpass traditional human capabilities. The findings highlight that increased software complexity does not eliminate the need for clinical supervision. The review confirms that human oversight remains essential for the accurate interpretation of automated outputs in medical settings. The data suggest that the field is moving toward a future where automation and professional expertise coexist.

Conclusions:

Synthesis and Implications suggest that machine learning models will likely achieve superior performance metrics compared to traditional methods. The authors propose that integrating multidimensional data will expand the diagnostic capabilities of these systems. Experts anticipate that future architectures might reach performance levels exceeding current human benchmarks. However, the researchers emphasize that clinical deployment necessitates constant oversight by qualified professionals. The review highlights that software complexity does not replace the requirement for expert medical judgment. Authors maintain that human interpretation remains a cornerstone for safe patient care. The synthesis indicates that while automation improves efficiency, it cannot operate independently in sensitive environments. These implications underscore the balance between technological advancement and professional responsibility in modern medicine.

The researchers propose that these networks improve operational efficiency, such as attenuation correction, while simultaneously enhancing the accuracy of disease diagnosis and predictive modeling.

The authors identify large imaging data repositories as the primary resource enabling the development of increasingly sophisticated software platforms.

The authors suggest that human supervision is a technical necessity to ensure the appropriate application and clinical interpretation of results generated by complex networks.

The researchers indicate that integrating multidimensional datasets is the key factor that may allow these systems to reach superhuman levels of performance.

The authors describe a transition from basic operational processes to advanced predictive diagnostics over the last two decades of development.

The researchers propose that while these systems will reach high performance levels, they will remain dependent on professional guidance for safe medical practice.