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Post-proline cleaving enzyme in human cerebrospinal fluid from control patients and parkinsonian patients
1Department of Biochemistry, Nagoya University School of Medicine, Japan.
Biochemical Medicine and Metabolic Biology
|December 1, 1987
Abstract:
PPCE activity was found in human CSF by using a HPLC-fluorescence method. PPCE activity in CSF from control patients without neurological diseases was 2.19 +/- 0.78 (mean +/- SD) pmole (hr)-1.(ml)-1. PPCE activity in CSF from patients with Parkinson's disease was significantly decreased while PPCE activity in serum did not change significantly.