Related Experiment Video
Updated: Jul 18, 2026

07:27
Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
12.1K
[Bartonella henselae neuroretinitis in an adolescent]
María E Conde1, María E Antueno1, Florencia Palmieri2
1Unidad 6 de Clínica Pediátrica, Hospital de Niños Ricardo Gutiérrez, Ciudad Autónoma de Buenos Aires, Argentina.
Archivos Argentinos De Pediatria
|November 23, 2021
Summary
Neurorretinitis, a rare complication of cat scratch disease, can cause vision loss. A characteristic "macular star" finding in a teen
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neuro-ophthalmology
Background:
- Cat scratch disease (CSD) is caused by Bartonella henselae.
- Ocular manifestations, including neurorretinitis, occur in 1-2% of CSD patients.
- Ocular symptoms can precede or occur without systemic signs of infection.
Observation:
- A 14-year-old boy presented with decreased visual acuity and suspected optic neuritis.
- Ophthalmological examination revealed papilledema and a characteristic "macular star" in the left eye.
- The macular star is a hallmark sign suggestive of Bartonella henselae infection.
Findings:
- The clinical presentation and characteristic macular star led to the diagnosis of CSD.
- Serological testing confirmed the presence of Bartonella henselae infection.
- Prompt diagnosis allowed for appropriate management of the ocular manifestation.
Implications:
- This case highlights the importance of recognizing the macular star sign for diagnosing CSD-related ocular disease.
- Early diagnosis and treatment of CSD can prevent irreversible vision loss.
- Ophthalmologists should consider CSD in the differential diagnosis of optic neuritis and macular exudates.
Related Concept Videos
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Rabies
Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Encephalitis l: Introduction
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

