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Updated: Oct 12, 2025
09:58
Development, Characterization, and Evaluation of CAGE-based Ionic Liquid Systems for Transdermal Delivery
Published on: September 26, 2025
50
Recent advances in polymeric transdermal drug delivery systems
Farzaneh Sabbagh1, Beom Soo Kim1
1Department of Chemical Engineering, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea.
Summary
Transdermal drug delivery systems offer a safe and effective alternative to oral medications, minimizing side effects. This review explores various polymer patches and their mechanisms for enhanced drug delivery through the skin.
Area of Science:
- Pharmacology and Materials Science
- Drug Delivery Systems
- Biomedical Engineering
Background:
- Transdermal delivery is a preferred novel drug delivery system, bypassing gastrointestinal and hepatic metabolism.
- This method reduces the risk of liver dysfunction and gastrointestinal irritation.
- Advantages include sustained drug release, steady circulation, and passive diffusion.
Purpose of the Study:
- To review different types of polymer patches used in transdermal drug delivery.
- To analyze the advantages and disadvantages of various transdermal drug delivery methods.
- To discuss the mechanisms of transdermal drug delivery utilizing patches.
Main Methods:
- Comprehensive literature review of transdermal drug delivery systems and polymer patches.
- Analysis of studies on different transdermal delivery methods and their efficacy.
- Examination of the design, materials, manufacturing, and evaluation of transdermal patches.
Main Results:
- Transdermal patches, with historical roots, offer controlled drug administration.
- Various polymer patch types exist, each with specific benefits and drawbacks.
- Different mechanisms facilitate drug permeation through the skin via patches.
Conclusions:
- Transdermal drug delivery systems, particularly polymer patches, represent an advanced and effective technology.
- Careful consideration of design, materials, and manufacturing is crucial for successful transdermal patch development.
- This review provides insights into the diverse landscape of transdermal drug delivery via patches.
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