Chemical Reactions
Response Surface Methodology
Introduction to Chemical Reactions
Predicting Reaction Outcomes
Reaction Mechanisms
Reaction Rate
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Updated: Oct 12, 2025

Optimization of the Ugi Reaction Using Parallel Synthesis and Automated Liquid Handling
Published on: November 11, 2008
Shijing Ma1, Yunhe Wang2, Shouwei Zhang1
1School of Physical Education, Northeast Normal University, Changchun 130022, China.
This study introduces an enhanced Chemical Reaction Optimization (CRO) algorithm, improving efficiency and performance for complex optimization tasks. The novel approach demonstrates superior results compared to existing methods in benchmark tests and antenna array synthesis.
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