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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
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Reply to Letter to the Editor on "Synovial Absolute Neutrophil Count as a Superior Diagnostic Biomarker for Acute Periprosthetic Joint Infection in Hip and Knee Arthroplasty With Low-Virulence Organisms".

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Related Experiment Video

Updated: Oct 12, 2025

Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
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Silver Coatings in Reconstructive Orthopaedics: Basic Science and Clinical Rationale.

Bryce N Clinger1, Helmut D Link2, Dustin L Richter1

  • 1Department of Orthopaedic Surgery, University of New Mexico School of Medicine, Albuquerque, NM, USA.

Surgical Technology International
|November 24, 2021
PubMed
Summary

Silver coatings on prosthetic joints may reduce infection risk after hip and knee replacement surgery. However, optimal application and potential toxicity require further investigation for effective prosthetic joint infection prevention.

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Area of Science:

  • Orthopaedic surgery
  • Biomaterials science
  • Infectious disease prevention

Background:

  • Prosthetic joint infection (PJI) remains a significant complication after hip and knee arthroplasty.
  • Despite advances, PJI incidence has not decreased significantly in recent decades.
  • Silver coatings are explored to mitigate PJI risk due to silver's antimicrobial properties.

Purpose of the Study:

  • To review the current use of silver coatings in reconstructive orthopaedics.
  • To explore available types and coating techniques for endoprostheses.
  • To examine the basic science and clinical applications of silver coatings in PJI prevention.

Main Methods:

  • Literature review of silver coatings in orthopaedic materials.
  • Analysis of silver's antimicrobial properties and mechanisms.
  • Evaluation of clinical data on silver-coated prostheses for PJI prevention.

Main Results:

  • Silver exhibits antimicrobial properties and is used on orthopaedic materials and endoprostheses.
  • The optimal preparation, coating thickness, and mechanisms of action are not fully understood.
  • Silver toxicity is a critical consideration for its clinical application.

Conclusions:

  • Silver coatings are increasingly adopted for PJI prevention in hip and knee reconstructions.
  • Further research is needed to clarify optimal application methods and address toxicity concerns.
  • Silver coatings show potential for reducing prosthetic joint infections, but their use remains debated.